Structural Biology Core

The Structural Biology Core is a multi-user facility serving both the VCU campus and external research institutes. The core encompasses X-ray crystallography, Cryo-Electron Microscopy (Cryo-EM), and Nuclear Magnetic Resonance (NMR) facilities, and is also closely associated with the School of Pharmacy Molecular Modeling facility.

About

The Structural Biology Core provides access to state-of-the art equipment, offering researchers the capability to determine the 3D structure of macromolecules and macromolecular complexes. This yields a diverse array of information on their biological or physiological functions, and enables structure-based drug design, protein-ligand or DNA binding studies, testing mutational effects on target macromolecules, and finding the absolute stereochemistry of chiral compounds.

Additionally, the core offers training, technical support, and collaborative opportunities, which are crucial for structural biologists and other researchers studying the structure of biological macromolecules and other materials.

Acknowledge the Structural Biology core

All publications or research articles that include results, services or products generated by the VCU Structural Biology Core must include the following acknowledgment in the manuscript:

Services and products in support of the research project were generated by the Virginia Commonwealth University Structural Biology Core, supported in part, with funding from the NIH Shared Instrumentation Grant S10-OD021756 and/or the Virginia General Assembly Higher Education Equipment Trust Fund (HEETF).